CÁRIE DENTAL E O POTENCIAL PREVENTIVO DOS CANABINOIDES
DOI:
https://doi.org/10.58731/2965-0771.2025.118Resumo
Como as doenças bucais impactam a qualidade de vida globalmente, a Odontologia tem buscado evoluir para um cuidado mais integral, considerando corpo e mente. Nesse sentido, pesquisas sobre canabinoides têm avançado, especialmente após regulamentações como as da Agência Nacional de Vigilância Sanitária (Anvisa). Compostos da Cannabis sativa, com propriedades analgésicas, anti-inflamatórias e ansiolíticas, mostram-se promissores no tratamento de dores, doenças periodontais, cáries, mucosite e câncer bucal. O Sistema Endocanabinoide (SEC), que regula funções vitais e desempenha papel crucial na saúde bucal, influencia a incidência de inflamação e dor. Por isso, receptores CB1 e CB2, presentes em tecidos orais, têm potencial terapêutico em condições como síndrome da boca ardente e aftas. A cannabis medicinal surge, então, como alternativa à crise de opioides. A cárie dentária, associada a bactérias e hábitos alimentares, é a doença oral mais comum, afetando bilhões de pessoas. Portanto, estratégias preventivas e terapêuticas são essenciais para mitigar seus impactos. O biofilme dental, conhecido como placa bacteriana, é uma estrutura resistente que contribui para o desenvolvimento de cáries, reforça a importância da higiene bucal. Nesse contexto, a cannabis, redescoberta após avanços no estudo do SEC, oferece uma abordagem integrada à Odontologia. Seu uso amplia a visão do paciente como um todo, promovendo saúde sistêmica e bucal com potencial para tratamentos inovadores.
Palavras-chave: Sistema Endocanabinoide; Cannabis medicinal; Saúde bucal; doenças bucais; Biofilme dental.
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